I am a computational biologist with background in biotechnology and Associate Professor at the Dept. of Biotechnology and Biosciences, Milano-Bicocca University. I lead a research group studying how co- and post- transcriptional events shape gene expression programs. We employ an interdisciplinary approach combining cutting edge experimental and computational methods, including the profiling of nascent and modified RNA, single-molecule Nanopore sequencing, and mathematical modelling (https://www.iit.it/it/web/genomic-science/pelizzola).
Research center
CGS@SEMM
About
Education
Title: PhD in Complexity in Post-Genomic Biology
Institute: University of Torino
Location: Torino
Country: Italy
From: 2004 To: 2006
Title: Master in Bioinformatics
Institute: Milano-Bicocca University
Location: Milano
Country: Italy
From: 2002 To: 2003
Title: Master’s degree in Industrial Biotechnologies
Institute: Milano-Bicocca University
Location: Milano
Country: Italy
From: 1995 To: 2001
Experience External
Title: Postdoctoral Research Associate
Institute: Salk Institute for Biological Science
Location: La Jolla, CA
Country: USA
From: 2009 To: 2011
Title: Postdoctoral Research Associate
Institute: Yale University
Location: New Haven , CT
Country: USA
From: 2007 To: 2009
Top Publications
2017
De Pretis S., Kress T.R., Morelli M.J., Sabo A., Locarno C., Verrecchia A., Doni M., Campaner S., Amati B., Pelizzola M.
Integrative analysis of RNA polymerase II and transcriptional dynamics upon MYC activation
Genome Research, vol. 27, (no. 10), pp. 1658-1664
2014
Sabo A., Kress T.R., Pelizzola M., De Pretis S., Gorski M.M., Tesi A., Morelli M.J., Bora P., Doni M., Verrecchia A., Tonelli C., Faga G., Bianchi V., Ronchi A., Low D., Muller H., Guccione E., Campaner S., Amati B.
Selective transcriptional regulation by Myc in cellular growth control and lymphomagenesis
Nature, vol. 511, (no. 7510), pp. 488-492
2011
Lister R., Pelizzola M., Kida Y.S., Hawkins R.D., Nery J.R., Hon G., Antosiewicz-Bourget J., Ogmalley R., Castanon R., Klugman S., Downes M., Yu R., Stewart R., Ren B., Thomson J.A., Evans R.M., Ecker J.R.
Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells
Nature, vol. 471, (no. 7336), pp. 68-73
2009
Lister R., Pelizzola M., Dowen R.H., Hawkins R.D., Hon G., Tonti-Filippini J., Nery J.R., Lee L., Ye Z., Ngo Q.-M., Edsall L., Antosiewicz-Bourget J., Stewart R., Ruotti V., Millar A.H., Thomson J.A., Ren B., Ecker J.R.
Human DNA methylomes at base resolution show widespread epigenomic differences
Nature, vol. 462, (no. 7271), pp. 315-322
All Publications
2024
Maestri S., Furlan M., Mulroney L., Tarrero L.C., Ugolini C., Pozza F.D., Leonardi T., Birney E., Nicassio F., Pelizzola M.
Benchmarking of computational methods for m6A profiling with Nanopore direct RNA sequencing
Briefings in Bioinformatics, vol. 25, (no. 2)
2024
Kumar N.H., Kluever V., Barth E., Krautwurst S., Furlan M., Pelizzola M., Marz M., Fornasiero E.F.
Comprehensive transcriptome analysis reveals altered mRNA splicing and post-transcriptional changes in the aged mouse brain
Nucleic Acids Research, vol. 52, (no. 6), pp. 2865-2885
2024
Dermentzaki G., Furlan M., Tanaka I., Leonardi T., Rinchetti P., Passos P.M.S., Bastos A., Ayala Y.M., Hanna J.H., Przedborski S., Bonanomi D., Pelizzola M., Lotti F.
Depletion of Mettl3 in cholinergic neurons causes adult-onset neuromuscular degeneration
Cell Reports, vol. 43, (no. 4)
2024
Coscujuela Tarrero L., Fama V., D'Andrea G., Maestri S., de Polo A., Biffo S., Furlan M., Pelizzola M.
Nanodynamo quantifies subcellular RNA dynamics revealing extensive coupling between steps of the RNA life cycle
Nature Communications, vol. 15, (no. 1)
Article
Journal
2022
Leone M., Galeota E., Masseroli M., Pelizzola M.
Identification, semantic annotation and comparison of combinations of functional elements in multiple biological conditions
Bioinformatics, vol. 38, (no. 5), pp. 1183-1190
